The best thing you could do is take a vacation now and come back around the 19th when v5.1 will be launched.
According to the roadmap, tweets and remarks here and there on the forums v5.1 is going to show significant speed bump with partial (on demand)
All marketing bla-bla I know, but for instance the RadControls used will be Q2 2012 which means no double loading of jQuery and actual compressed resources. (maybe not an 'initial visit' enhancement example, but you see they'll measurably speed up Sitefinity).
Once that's released you can start looking again in things like caching & keeping the site warm...