My permission is totally not needed, don't be silly - we're all one community of Sitefinity people no? The more input and insight there is, the better the end result will be...
Currently sitefinity's Mobile add-on offers 2 major features:
- Mobile Preview
- Responsive design rule-based setup.
As for 'Mobile Preview' that's a really cool end-consumer feature that allows content editors to preview and make changes when a site is viewed on a tablet or phone. That will work out-of-the-box with whatever setup you have, even if you've not setup any responsive rules.
The responsive rule setup are getting more advanced with each release of Sitefinity. First they offered global rule sets, now they offer them template based already. If I'm not mistaking the v6 roadmap has even further mobile enhancements up its sleeve.
The rule sets basically define the 'when' and 'what' for your site. And here comes the crucial part: it allows you to set circumstances to offer 'internal responsive' transform (1 row, 2 columns > 2 rows, 1 column) or assign unique .css files (iphone retina specifc css files). So it's not just a nice interface for media-queries.
Getting back to boilerplate/bootstrap.
Like I said before, the 'boilerplate' theme/template will work 100% out-of-the-box with the mobile add-on, because it sets you up properly, without having media-queries or responsive design rules of its own.
The 'Bootstrap' theme/template is somewhat trickier, because Twitter bootstrap has media-queries of its own and its rule-set differs from Sitefinity's default.
So while the 'Mobile preview' function will work 100% out-of-the-box it's rule-sets are incompatible (sf_cols vs row-fluid classes).
If you're planning on using Twitter Bootstrap, then you have to 'ignore' it's internal responsive transforms (1 row, 2 columns > 2 rows, 1 column) unless you really want to go deep and make them compatible.
Instead of having to setup all these columns transfers, bootstrap will handle them for you automatically and for you all that is left to do is to enhance rule-sets with external css if you specifically want to target and enrich certain devices.
Because of it's class difference, sitefinity lay-out widgets aren't compatible with bootstrap widgets as said before. In order to make those compatible, you'll have to tweak them - or tweak Bootstrap so that it will apply the same functionality to .sf_colsOut .sf_2cols_1_25 + .sf_colsIn .sf_2cols_1in_25 as it does to .span4.
I'll see what I can do in making the layout widgets compatible with Bootstrap this week.