Hello Seth Cleaver,
You are right that currently it is way too complicated to configure the settings for all the editor instances in the same way. We have had similar requests and have discussed the possibilities for improving this functionality in one of our next releases and more specifically, the ability to enable and disable tools for the editor from the UI.
As for setting properties like NewLineBr="False"
across all editors in the admin, with the current implementation this is not possible. You have to edit the corresponding templates (ControlPanelEdit.aspx and ControlPanelInsert.aspx for each module) and then copy the whole folder for your custom providers. There is no simpler way, unfortunately. We are really sorry for the inconvenience this has been causing.
the Telerik team