18 Jul 2012
23 Mar 2011
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I think what they mean is that performance-wise, SQL Express is not designed to maintain high server loads from a busy website. It's great for small sites on shared hosting, and I don't believe there is anything in those limitations that will prevent Sitefinity from running.
I think old versions limited incoming connections but I think that has been done away with. Still, if your site explodes with popularity, performance might suffer, not because of Sitefinity but because SQL Express is not designed to support that much traffic.
hope this is helpful!