We don't remember what were the exact problems for not upgrading to the build 2525, however they we re not related to the Visual Studio integration. The issues appered on runtime.
Actually, I don't think, that the exact installed Nolics version makes sense for generating the persistanse classes, the logic behind is probably the same in the both versions. For instance, we have created db classes with the lates Nolics beta release for Visual Studio 2008, and then compiled them with the version 2522, without any problems.
However, your problem could be related to something, which we haven't run against yet.
Please let us know how can we help you further.
the Telerik team