You can use Telerik.Sitefinity.Security.UserManager - Represents an intermediary between users and membership data providers. and Telerik.Sitefinity.Security.Model.User class - The persistent membership user class used by OpenAccess membership provider.
// getting user
var manager = Telerik.Sitefinity.Security.UserManager.GetManager();
var user = manager.GetUsers().Where(u => u.FirstName ==
// creating user, setting properties
var newUser = manager.CreateUser(
(status == System.Web.Security.MembershipCreateStatus.Success)
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